Protein Details: Aquaporin PIP1-1

Protein ID

ICDB_Pro_0660

Protein Name

Aquaporin PIP1-1

Gene Name

PIP1-1; PIP1A; At3g61430; F2A19.30

Organism

Arabidopsis thaliana (Mouse-ear cress)

Length

286 amino acids

AlphaFoldDB

AF-P61837-F1-model_v4.pdb

Function

Water channel required to facilitate the transport of water across cell membrane. Its function is impaired by Hg(2+).

Sequence

MEGKEEDVRVGANKFPERQPIGTSAQSDKDYKEPPPAPFFEPGELSSWSFWRAGIAEFIATFLFLYITVLTVMGVKRSPNMCASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTRALYYIVMQCLGAICGAGVVKGFQPKQYQALGGGANTVAHGYTKGSGLGAEIIGTFVLVYTVFSATDAKRNARDSHVPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKDHSWDDHWVFWVGPFIGAALAALYHVVVIRAIPFKSRS

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Widely expressed; Expressed in roots; above ground and in flower buds.

DOI ID

10.1046/j.1365-313x.1994.6020187.x; 10.1038/35048706; 10.1111/tpj.13415; 10.1126/science.1088305; 10.1186/gb-2001-3-1-research0001; 10.1042/bj20060569

RefSeq

NP_001078323.1; NP_191702.1